GOAD, Mary Elizabeth Pecquet,SCHRIER, Denis,PIERCE, Allen Richard
申请号：
AU2013206500
公开号：
AU2013206500A1
申请日:
2013.06.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013206500A120130711.pdf#####Abstract The present invention is directed to methods and compositions for systemic delivery of minimally-soluble bioactive agents such as, but not limited to, proteins of the TGF-0 superfamily. According to the invention, an exemplary bioactive agent is 5 BMP-7 The invention further provides for minimally-invasive systemic treatment of skeletal disorders such as osteoporosis as well as minimally-invasive systemic treatment of injured or diseased non-mineralized tissues and organs such kidneys. Practice of the invention eliminates adverse side effects at the site of intravascular delivery of the bioactive agent. 4422804_1 (GHMatlers) P87734 AU.1
