Fang Fang,David Wurtman,Ron Moss,Michael P. Malakhov
申请号：
US15865217
公开号：
US20180140683A1
申请日:
2018.01.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.
