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Peptide or peptide complex binding to 2 integrin and methods and uses involving the same
专利权人:
SANOFI
发明人:
CORVEY CARSTEN,BLUM HORST,CAMERON BÉATRICE,DABDOUBI TARIK,DECARY STEPHANIE,BAURIN NICOLAS,PAPIN DAVID,LANGE CHRISTIAN
申请号:
NZ62959511
公开号:
NZ629595A
申请日:
2011.08.30
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Discloses a peptide, peptide complex or antibody wherein said peptide or peptide complex, antibody or fragment specifically binds to the I-domain of a human a2-integrin, said antibody or fragment comprising a heavy chain variable region (VB) domain and a light chain variable region (VL) domain, wherein said antibody or fragment cross-reacts with a non-human primate a2-integrin but does not cross-react with a non-primate a2-integrin. Further discloses where the antibody competes with a reference antibody for binding to the I-domain of a human a2-integrin, wherein the antibody is encoded on the plasmid deposited under DSMZ under accession No. DSM 23944, DSM 23946 or No. DSM 23945.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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