A POLYVALENT COMBINED IMMUNISING AND/OR THERAPEUTIC PREPARATION FOR USE IN BACTERIAL INFECTIONS OR FOOD POISONING, PARTICULARLY SALMONELLOSIS, A METHOD FOR PRODUCTION OF THIS PREPARATION, ITS USE AND A VACCINE COMPRISING THIS PREPARATION
The invention relates to a polyvalent, combined immunising and/or therapeutic preparation for use in bacterial infections and food poisoning, particularly salmonellosis, comprising inactivated Salmonella sp. strain with antibodies bound thereto, characterized in that the said antibodies are selected so as to bind to the antigenic epitopes in structures of repeating O- specific units in the basic groups of Salmonella bacteria, which are responsible for the principle of reaction with the host immune system, while not blocking the epitopes responsible for the recognition of Salmonella serotype, wherein the inactivated bacteria are bacteria of the Salmonella genus enterica species, subspecies: enterica, salamae, arizonae and/or diarizonae, houtenae, Indica. The invention relates also to a method for production of this polyvalent, combined immunising and/or therapeutic preparation and a vaccine against salmonelloses comprising said preparation.
