A retractable universal safety scalpel (10) comprising a handle (12) having a proximal section (18) and a distal section (20) with a longitudinally extending bore (14) defining a housing (16) a blade carrier element (26) having mid-section (28), proximal end and a distal end on which is secured a blade (30) slidably mounted within said housing (16) being capable of getting exposed from the end of distal section (20) of said housing first (32) and second (34) slider elements secured to said blade carrier element (26) through a recess (36) formed in the said handle (12) extending from the forward end closer to the said opening to the rear end closer to the distal section of the said handle (12) in a slidable arrangement with the said housing (16) and extending externally in an axial direction of said housing (16) to move said blade carrier element (26) moving the said blade (30) from an un-exposed pre-use position to an exposed in-use position and to an after-use position capable of covering and locking permanently the said blade (30) completely within the said housing (16) of the said handle (12) a plurality of locking means is provided in the said housing (16) to enable locking of the blade (30) in an un-exposed pre-use position to an exposed in-use position and to an after-use position capable of covering and locking permanently the said blade (30) wherein the said housing (16) being provided with lock cooperating mechanisms at three positions thereon corresponding to pre-use, in-use and post-use disposal stages, said lock cooperating mechanisms cooperating with the respective locking means provided thereon.