CATENA RUIZ JUAN LORENZO,SERRA COMAS CARME,REY PUIGGROS OSCAR,ANTOLIN HERNANDEZ ALBERT,MONLLEO MAS ESTER
申请号：
IN9955/DELNP/2011
公开号：
IN2011DN09955A
申请日:
2011.12.16
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The compounds of formula (I) are derived from perhydroquinoline and perhydroisoquinoline and are useful as active pharmaceutical ingredients for the prophylaxis or treatment of diseases caused by 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSDl) enzyme-associated disorders, such as glaucoma, elevated ocular pressure, metabolic disorders, obesity, metabolic syndrome, dyslipidemia, hypertension, diabetes, atherosclerosis, Cushings syndrome, psoriasis, rheumatoid arthritis, cognitive disorders, Alzheimers disease or neurodegeneration.
