#$%^&*AU2014274536A120150122.pdf#####ABSTRACT The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof. B1 A Y( )X-- D-E (1) B2 6030710 1 (GHMatters) P85519.AU.1 JENNYP