The United States of America; as Represented by the Secretary; Department of Health and Human Services
发明人:
Chiorini, John
申请号：
AU2013308470
公开号：
AU2013308470A1
申请日:
2013.08.30
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention relates to a gene transfer-based method to protect a subject from Sjogrens syndrome. The method comprises administering to the subject an AAV virion comprising an AAV vector that encodes aquaporin- 1 (AQP-1) protein. Also provided are AQP-1 proteins and nucleic acid molecules that encode such proteins. Also provided are AAV vectors and AAV virions that encode an AQP- 1 protein.
