Richard Chou;Daniel A. Albert;Constance E. Brinckerhoff
发明人:
Richard Chou,Constance E. Brinckerhoff,Daniel A. Albert
申请号：
US13641173
公开号：
US20130035357A1
申请日:
2011.04.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is methods for inhibiting collagen destruction in joints of osteoarthritis patients. The methods are based on use of rexinoid compounds, in particular bexarotene, and their activity to inhibit synthesis of matrix metalloproteinases (MMPs) in affected tissue.
