Wolfgang Aehle,David A. Estell,Ronaldus W. J. Hommes,Brian E. Jones,Marc Kolkman,Chris Leeflang,Hiroshi Oh,Ayrookaran J. Poulose,Andrew Shaw,Wilhelmus A. H. Van der Kley,Leonardus P. M. Van Marrewijk
申请号：
US13888300
公开号：
US08865449B2
申请日:
2013.05.06
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.
