BAYLINK, David J.,LAU, Kin-Hing William,QIN, Xuezhong
申请号:
AU2014201381
公开号:
AU2014201381B2
申请日:
2014.03.11
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014201381B220140515.pdf#####ABSTRACT Gene-modified, inflammation-specific monocytes that comprise a 1-alphahydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation-specific macrophages. Gene-modified, inflammation- specific macrophages that comprise a 1-alpha-hydroxylase gene. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering genemodified, inflammation-specific monocytes that comprise a 1-alpha-hydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation- specific macrophages.