The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and/or a saccharide. These compositions are useful in treating epilepsy and bipolar disorder, particularly for patients with dysphagia, and to improve compliance with bipolar patients.本發明組合物之組成包含治療有效量之包含樂命達(lamotrigine)之粒子與包含崩解劑、及糖醇及/或糖類之顆粒的組合。該等組合物可用於治療癲癇及雙相情感障礙,尤其用於具有吞嚥困難之患者,及用於提高雙相情感障礙患者之依從性。(無元件符號說明)