Richard W. Compans,Chinglai Yang,Qizhi Yao,Sang-moo Kang
申请号:
US14703342
公开号:
US09957300B2
申请日:
2015.05.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Briefly described, virus-like particles, methods of preparing virus-like particles, immunogenic compositions that include virus-like particles, and methods of eliciting an immune response using immunogenic compositions that include virus-like particles are described herein. A virus-like particle (VLP) can include a viral core protein that can self assemble into the VLP core and at least one viral surface envelope glycoprotein expressed on the surface of the VLP. The VLP can also optionally include at least one adjuvant molecule expressed on the surface of the VLP.