ANTI-NOTCH3 AGONIST ANTIBODIES AND THEIR USE IN THE TREATMENT OF NOTCH3-RELATED DISEASES

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专利权人:

GENENTECH; INC.

发明人:

LI, KANG,ZHOU, BIN-BING STEPHEN,WU, WENJUAN,FUNG, SEK CHUNG,SINGH, SANJAYA

申请号：

NZ57660507

公开号：

NZ576605A

申请日:

2007.10.18

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed are antibodies that bind to Notch3 by binding to an epitope in SEQ ID NO: 10 and activating Notch 3-mediated signalling. The antibodies can be used for treating a neurodegenerative disease, in particular CADSIL, familial hemiplegic migraine (FHM), familial paroxytic ataxia or Alagille syndrome.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/