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Rapid selection method for HIV gp-120 variants
专利权人:
Laboratorios del Dr. Esteve, S.A.;Fundacio Privada Institut de Recerca de la Sida - Caixa
发明人:
Yuste Herranz, Maria Eloisa,Sanchez Merino, Victor,Ferreira, Carolina
申请号:
AU2012219418
公开号:
AU2012219418B2
申请日:
2012.02.24
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The invention relates to a method for rapid immunogen selection (RIS) based on the binding a library of recombinant viruses containing randomized HIV gp120 variants of a surface polypeptide displayed to said neutralizing antibodies. The invention relates as well to the use of the HIV gp120 immunogens isolated according to the RIS method of the invention in medicine for the treatment of diseases caused by a virus and in diagnosis for the identification of neutralizing antibodies in a patient.
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