PROBLEM TO BE SOLVED: To provide medicine and food for inhibiting cardiac fibrosis, ventricular wall hypertrophy, cardiac hypertrophy and heart failure.SOLUTION: The medicine and food include luteolin represented by formula (1) or a derivative thereof as an active ingredient. In the formula, R1 to R4 each independently represents a hydrogen atom, an alkyl group, a sulfo group, or a sugar residue.COPYRIGHT: (C)2013,JPO&INPIT【課題】心臓の線維化、心室壁肥厚、心肥大及び心不全を抑制する医薬及び食品の提供。【解決手段】下記式で示されるルテオリン又はその誘導体を有効成分とする医薬及び食品。(式中、R1~R4は、それぞれ独立して、水素原子、アルキル基、スルホ基又は糖残基を示す)【選択図】なし