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FORME CRISTALLINE DE COMPOSÉS DE TYPE IMIDAZOLONE, ET PROCÉDÉ DE PRÉPARATION, COMPOSITION PHARMACEUTIQUE ET UTILISATION ASSOCIÉS
专利权人:
Ltd.;Foreland Pharma Co.
发明人:
申请号:
EP16886929.5
公开号:
EP3412291A4
申请日:
2016.01.26
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to the crystal form of imidazolone type compounds, and a preparation method, pharmaceutical composition and use thereof, and falls within the field of pharmaceutical compound crystals. The crystal form provided by the present invention has a good stability, comprising good stability under the three extreme conditions of high temperature, high humidity and strong illumination, and can also maintain a good stability during the tablet compressing process. The crystal form provided by the present invention has good absorption and metabolism properties in vivo, comprising the drug concentration of blood, the drug concentration-time curve AUC, the half-life period, etc. In addition, the dissolving rate of the crystal form of the present invention is improved, wherein same is beneficial for the applications thereof in preparations.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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