CAIN, JENNIFER ANNE,WANG, MIN,KAPOUN, ANN M.,HOEY, TIMOTHY C.
申请号:
CA2864197
公开号:
CA2864197A1
申请日:
2012.11.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides the identification and characterization of NOTCH mutations associated with enhanced receptor signaling. The present invention provides methods and kits for using the same. The present invention further provides methods of treating cancer in a patient having a solid tumor, wherein the solid tumor cells comprise an elevated level of NOTCH ICD.