ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING CELL BASED TECHNOLOGIES &； THERAPIES (A4TEC) AS
发明人:
Cristiana DA MOTA MARTINS GONÇALVES,Simone DOS SANTOS SILVA,Fátima Raquel AZEVEDO MAIA,Hajer RADHOUANI,Joaquim Miguel ANTUNES CORREIA DE OLIVEIRA,Rui Luís GONÇALVES DOS REIS
申请号：
US16620823
公开号：
US20200188486A1
申请日:
2018.06.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to a composition for the release of the bioactive substance comprising: sucrose acetate isobutyrate dissolved in an ionic liquid and an additive selected from the list consisting of: chitin, silk fibroin, cellulose, alginate, chitosan, gellan gum, dextrin, collagen, guar gum, carregeenan, heparin, kefiran, or mixtures thereof. By taking advantage of the properties of an ionic liquid (IL), in particular 1-butyl-imidazolium acetate (BMIMAc), it was possible to achieve a good dissolution of SAIB, which combined with chitin and/or silk, natural polymers, allows the development of the structures with different shape and sizes.
