A device includes a stent scaffold structure supporting a patch on an interior surface thereof. The device may be used to produce a neovalve in a percutaneous minimally invasive manner. Exemplary methods include implanting the device, permitting a growth layer to form over at least a portion of the patch, and separating the patch from the stent scaffold thereby forming a slit or gap in the vessel wall to act as a valve similar to the surgical neovalve.