JU YOUNG LEE,KEUN-HO RYU,JAE-SUN KIM,YONG-HYUK KIM,DONG CHUL SHIN,BONG-YONG LEE,SANG-HWAN KANG,HYUN JUNG LEE,HOECHUL JUNG,YOUNG AH SHIN,EUISUN PARK,JAESEUNG AHN,HUN-TAEK KIM,JE HO RYU
申请号：
PT12811865
公开号：
PT2731949T
申请日:
2012.07.13
申请国别(地区):
PT
年份:
2018
代理人:
摘要：
The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4)； a pharmaceutical composition comprising same as an active ingredient； and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.
