#$%^&*AU2007201562B220120712.pdf#####ABSTRACT A medical instrument includes a flexible tube, a distal member, a flexible endeffector activation wire, a proximal member, and a flexible first cable. The distal member is connected to the distal tube portion. The activation wire is positioned within the tube. The proximal member is attached to the tube. The first cable is positioned outside the tube, is substantially transversely constrained by the proximal member, and has a first distal cable portion attached to the distal member. Lengthwise translation of the first cable articulates the distal member with respect to the proximal member. Another instrument includes a drive screw which articulates an end effector (e.g., a grasper) pivotally connected to a tube. An additional instrument includes a drive screw which articulates a distal medical instrument member pivotally connected to a tube. A medical end effector (e.g., a snare) is positionable in a lumen of the distal medical instrument member.1/10 coN
