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Methods for reducing or preventing growth of tumors resistant to EGFR and/or ErbB3 blockade
专利权人:
Inc.;Regeneron Pharmaceuticals
发明人:
Daly, Christopher,Castanaro, Carla,Zhang, Wen,Thurston, Gavin
申请号:
AU2016366521
公开号:
AU2016366521A1
申请日:
2016.12.09
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides methods for inhibiting or attenuating the growth of a tumor that is resistant to a blockade of EGFR, which include administering an EGFR inhibitor, an EGFR inhibitor and a FGFR inhibitor, or an EGFR inhibitor, an FGFR inhibitor and an ErbB3 inhibitor to a subject having a tumor that is or may become resistant to the blockade of EGFR. Blockade of EGFR, FGFR and/or ErbB3 may be effectuated using target specific antibodies or fragments thereof, small molecule tyrosine kinase inhibitors or a combination thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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