THE UNIVERSITY OF QUEENSLAND;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF THE BOARD OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
发明人:
Luke O'Neill,Rebecca Coll,Matthew Cooper,Avril Robertson,Kate Schroder
申请号：
US15551264
公开号：
US10538487B2
申请日:
2016.02.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
