Use of a composition for treating Alzheimer's disease, osteoporosis, sleep apnea, erectile dysfunction, McArdle disease, or a carbohydrate metabolism disorder, or for reducing aging or fatigue. The composition includes a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5&prime；-monophosphate-activated protein kinase activator； a second agent that possesses anti-inflammatory activity； and a third agent that possesses serotonin activity.
