MAN CORNELIA WING YIN,WAI NORMAN FUNG MAN,WAI BENJAMIN CHI YIN,WONG BING LOU
申请号：
IN201627039769
公开号：
IN201627039769A
申请日:
2016.11.22
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Cells within liver tumour mass comprise a unique set of proteins/tumour antigens when compared to the normal liver tissues epithelial cells juxtaposed to the tumour. The presence of tumour antigens couples the production of auto antibodies against these tumour antigens. The present invention relates to the identification and elucidation of a protein set that can act as a novel marker set for liver cancer diagnosis and prognosis. Specifically it relates to a kit that enables diagnostic and prognostic measurement of auto antibodies in serum of liver cancer patients. The present invention provides a non invasive specific sensitive and cost effective detection and quantification method by evaluating a set of validated liver cancer proteins/tumour antigens which includes Bmi 1 VCC1 SUMO 4 RhoA TXN ET 1 UBE2C HDGF2 FGF21 LECT2 SOD1 STMN4 Midkine IL 17A or IL26 to complement the conventional diagnostic methods.
