AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;University of Tartu
发明人:
Lisa Fong Poh Ng,Yi Hao Chan,Andres Merits,Age Utt
申请号:
US16484277
公开号:
US20190359656A1
申请日:
2018.02.07
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention generally relates to polypeptides, polynucleotides, expression vectors, infectious clones, virus particles and immunogenic compositions of recombinant alphaviruses which can be used as vaccines. The present disclosure also relates to methods for eliciting an immune response against alphavirus infection using the immunogenic composition comprising the alphavirus mutants described herein.