PARK, SOON JAE,CHUNG, HYE-SHIN,LEE, SUNBAE,BYUN, MINSOO
申请号:
CA3018691
公开号:
CA3018691A1
申请日:
2017.03.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to: an antibody-drug conjugate in which a modified antibody, containing a motif of a specific structure at an end of the antibody, is coupled to a drug through a linker; and a composition containing the same and, specifically, to: a modified antibody-drug conjugate (mADC) comprising a modified antibody coupled to the C-terminus of heavy chain or light chain so as to have a remarkably increased drug conjugation yield; and a composition containing the same.