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Improved Process for the Preparation of Oxidized Phospholipids
专利权人:
Vascular Biogenics Ltd.
发明人:
Halperin, Gideon,Kovalevski-Ishai, Eti
申请号:
AU2011265448
公开号:
AU2011265448A1
申请日:
2011.12.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2011265448A120120119.pdf#####ABSTRACT Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby.
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