Arizona Board of Regents on behalf of Arizona State University
发明人:
James ADAMS,Dae-Wook KANG,Rosa KRAJMALNIK-BROWN
申请号:
US15290798
公开号:
US20170360848A1
申请日:
2016.10.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD) by restoring an ASD patient's gut microbiota. These methods can be used with ASD patient with or without ongoing gastrointestinal symptoms. Provided here is a method for modulating the abundance of one or more gut microorganisms in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a pharmaceutical composition comprising a fecal microbe preparation to achieve at least a 2-fold change of the abundance of said one or more gut microorganisms, wherein said one or more gut microorganisms are selected from the group consisting of Bifidobacterium, Prevotella, Desulfovibrio, Copprococcus, Clostridium, and Bacteroides.