The purpose of the present invention is to provide a combined pharmaceutical composition for prophylaxis and/or treatment of dyslipidemia status including atherosclerosis, hypercholesterolemia, HDL hypolipoproteinemia in a mammal including human, and the combined use of the agents. The pharmaceutical composition for prophylaxis and/or treatment of dyslipidemia and the like comprises a) a compound represented by the following general formula (1) (wherein, the symbols are same as those defined in the present specification), or a salt thereof, or a solvate thereof, and b) an inhibitor of cholesterol adsorption.本發明之課題為提供在包含人類之哺乳動物中，用於預防及/或治療如動脈粥樣硬化症、高膽固醇血症、低HDL血症之脂質異常症狀態之組合醫藥組成物及藥劑之併用。由含有a)下述通式(1)(式中，各符號與說明書中記載者同意義)表示之化合物、其鹽或該等之溶劑合物及b)膽固醇吸收抑制劑組成之脂質異常症等之預防及/或治療用醫藥組成物。
