NOVEL COMPOUNDS CAPABLE OF ANTAGONIZING ISLET AMYLOID POLYPEPTIDE (IAPP) INDUCED BETA-CELL DAMAGE AND IMPAIRED GLUCOSE TOLERANCE

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专利权人:

Neurimmune Holding AG;University of Zurich

发明人:

Jan GRIMM,Fabrice HEITZ,Fabian WIRTH,Tobias WELT

申请号：

US16705031

公开号：

US20200231667A1

申请日:

2019.12.05

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced β-cell damage and impaired glucose tolerance winch are symptoms typically associated with diabetes mellitus type 2 (T2D).

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中国工程科技知识中心

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