A hemorrhoid treatment device (100) for treating hemorrhoids in anorectal region is described. The hemorrhoid treatment device (100) includes a ligation unit (104), a pressure generation system, a control switch (122), and an actuator (108). The ligation unit (104) is inserted into a patient body to perform hemorrhoid ligation. The ligation unit (104) includes a ligation unit tip (106) loaded with a ligature and placed over a hemorrhoid tissue. The pressure generation system generates a controlled pressure and the control switch (122) actuates the pressure generation system to generate a partial vacuum inside a suction channel (118), which is fluidly coupled with the ligation unit tip (106). The partial vacuum aspirates the hemorrhoid tissue to expose a neck of the tissue and a ligation element (130) is actuated on pressing the actuator (108) for deploying the ligature on the neck of the hemorrhoid tissue.