CROMIE, KAREN,DOMBRECHT, BRUNO,ETTENBERG, SETH,KOLKMAN, JOOST,LI, JING,MEERSCHAERT, KRIS,STOVER, DAVID RAYMOND,ZHANG, JINGXIN
申请号：
MYPI 2012003428
公开号：
MY156337A
申请日:
2011.02.11
申请国别(地区):
MY
年份:
2016
代理人:
摘要：
THE PRESENT INVENTION RELATES TO AMINO ACID SEQUENCES THAT ARE DIRECTED AGAINST TRAIL CELL SURFACE RECEPTOR 2 (HEREIN ALSO “DR5”), AS WELL AS TO COMPOUNDS OR CONSTRUCTS THEREOF, AND IN PARTICULAR PROTEINS AND POLYPEPTIDES AND NUCLEOTIDES THAT ENCODE THEM (REFERRED TO HEREIN IN THEIR ENTIRETY AS “NB AGENTS”) AND FRAGMENTS THEREOF, AND PHARMACEUTICALLY EFFECTIVE VARIANTS THEREOF, AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF DR5 ASSOCIATED DISEASES AND DISORDERS. THE MOST ILLUSTRATIVE DRAWING IS FIG. 6B
