KAPP GREGORY,SERWER LAURA,LEMOAN NATACHA,CARY STEPHEN P L
申请号:
IN6436/DELNP/2015
公开号:
IN2015DN06436A
申请日:
2015.07.21
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The invention provides polymeric H NOX proteins for the delivery of oxygen with longer circulation half lives compared to monomeric H NOX proteins. Polymeric H NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H NOX proteins as radiosensitizers for the treatment of brain cancers.