Ashwell, Susan,Campbell, Ann-Marie,Caravella, Justin Andrew,Diebold, R. Bruce,Ericsson, Anna,Gustafson, Gary,Lancia, David R.,Lin, Jian,Lu, Wei,Wang, Zhongguo
申请号:
HRP20200666
公开号:
HRP20200666T1
申请日:
2020.04.24
申请国别(地区):
HR
年份:
2020
代理人:
摘要:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: (I) where A, U, W1, W2, W3, R1-R6, and R9 are described herein.