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METHOD FOR RESTORING A SOLID FORM OF PHARMACEUTICAL COMPOSITION
专利权人:
ЮСБ БИОФАРМА СПРЛ (BE);ЭВЕОН (FR)
发明人:
ПЭЙЕ-БЮРЕН Ксавье (FR)
申请号:
RU2016133973
公开号:
RU2016133973A
申请日:
2015.01.20
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
The invention relates to a process for reconstitution of a solid form of a pharmaceutical composition, comprising the following successive steps: (i) providing the solid form of the pharmaceutical composition in a sealed container, the pressure within the container being an initial pressure (pi,) comprised between 0.5 Pa and 1.2×105 Pa; (ii) at a first time point (t0) introducing the solvent into said sealed container and maintaining the resulting pressure (pr) within the container during a controlled time Δt1; and (iii) at a second time point (t2) increasing the pressure within the container to a controlled pressure (p2) higher than said resulting pressure (pr) until complete reconstitution.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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