JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH
发明人:
Govindaraju THIMMAIAH,Shivaprasad MANCHINEELLA
申请号:
US16077391
公开号:
US20200155726A1
申请日:
2017.02.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to the field of biomaterials, tissue engineering and regenerative medicine. Particularly, the present disclosure relates to biomaterial composite and preparation of various scaffold formats using the composite. The disclosure provides for preparation of biomaterial composite comprising silk fibroin and melanin, preparation of scaffolds with the biomaterial composite and its applications in tissue engineering, electrotherapy applications and regenerative medicine. In some embodiments, the silk fibroin is a peptide modified silk fibroin. The biomaterial composite of the present disclosure exhibits various advantages including but not limiting to enhanced antioxidant property, superior electroactive properties, improved myogenic cell differentiation, better cell growth and regeneration, and enhanced cell adhesion property.