Jan J. Lewandowski,Yubiao Liu,Roger Marchant,Tianhong Zhang,Yongxing Qiu,Mark A. Ruegsegger
申请号:
US13422150
公开号:
US09125969B2
申请日:
2012.03.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.