T cells for expression of chimeric antigen receptors and other receptors

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专利权人:

City of Hope

发明人:

Brown, Christine E.,Forman, Stephen J.

申请号：

AU2016297605

公开号：

AU2016297605A1

申请日:

2016.07.21

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Methods for preparing T cell populations useful for a variety of purposes requiring a highly active, long-lived T cell population. The T cell populations are enriched for: nave T cells (TN), memory stem cells (TSCM) and central memory T cells (TCM). These cell populations can be derived from peripheral blood mononuclear cells (PBMC) by both: 1) depleting unwanted cell populations such as CD14 expressing myeloid cells and CD25 expressing cells； and 2) enriching for CD62L expressing memory and nave T cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/