SHANGHAI HANSOH BIOMEDICAL CO., LTD.; LTD.;JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD.;JIANGSU HANSOH PHARMACEUTICAL GROUP CO.
发明人:
WU, SHENGHUA,LI, KAILONG,BAO, RUDI
申请号：
CA3019450
公开号：
CA3019450A1
申请日:
2017.04.06
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to an indoleamine 2,3-dioxygenase inhibitor having the structure of formula (I), a preparation method therefor, and an application. The IDO inhibitor is an N'-hydroxyl-N-phenylformamidine derivative, has high inhibitory activity on IDO, effectively inhibits IDO activity, and may also be used to inhibit patient immunosuppression. The inhibitor may be widely applied to treat or prevent cancers or tumours, viral infections, depression, neurodegenerative diseases, trauma, age-related cataracts, organ transplant rejection or autoimmune diseases, and has the potential to be developed into a new generation of immunosuppressors.
