William R. Baumbach,Darren R. Sherman,Robert S. Burgermeister
申请号:
US16115467
公开号:
US20180361124A1
申请日:
2018.08.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.