John T. Potts, Jr.;Harald Jueppner;Makoto Okazaki;Thomas J. Gardella
发明人:
Thomas J. Gardella,John T. Potts, Jr.,Harald Jueppner,Makoto Okazaki
申请号：
US13697249
公开号：
US09492508B2
申请日:
2011.05.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed.
