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Modified Cells Evoking Reduced Immunogenic Responses
专利权人:
Zhejiang University
发明人:
Lei Xiao,Haide Chen,Chun Cui,Yang Li,Di Cui
申请号:
US15616787
公开号:
US20170283769A1
申请日:
2017.06.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure describes composition, methods, and systems associated with a genetically modified stem cell. The modified stem cell includes a reduced amount of Major Histocompatibility Complex II (MHC II) as compared to a corresponding wild-type cell. Further, the modified cell has decreased immunogenicity as compared to the corresponding wild-type cell.
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