A method for purifying Mogroside V comprises passing a solution of a pre-prepared Siraitia grosvenori primary extract through a multi-column system including a plurality of columns, in series, packed with a porous adsorbent resin to provide at least one column having adsorbed mogrosides and eluting fractions with Mogroside V content from the at least one column having absorbed mogrosides to provide an eluted solution with Mogroside V content.
