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DÉRIVÉS AMINO-TRIAZINE ET COMPOSITION PHARMACEUTIQUE CONTENANT LESDITS DÉRIVÉS
专利权人:
LTD.;SHIONOGI & CO.
发明人:
KAI, HIROYUKI
申请号:
EP14810134
公开号:
EP3009432A4
申请日:
2014.06.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides novel compounds having a P2X 3 and/or P2X 2/3 receptor antagonistic activity. A compound of Formula (I): wherein R a and R b , and R d and R e are taken together to form oxo or the like; R 4a and R 4b are hydrogen or the like; n is 1 or the like; R 2 is aryl or the like; s and s' is 0 or the like; R 9 and R 9' are halogen or the like; R 20a and R 20b are hydrogen, alkyl or the like; u is 1 to 4; R 13 is hydrogen or the like, or its pharmaceutically acceptable salt.
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