EDUARDO MUNOZ BLANCO;VIVACELL BIOTECHNOLOGY ESPANA S.L.;GIOVANNI APPENDINO;MARIA LUZ BELLIDO CABELLO DE ALBA
发明人:
GIOVANNI APPENDINO,EDUARDO MUNOZ BLANCO,MARIA LUZ BELLIDO CABELLO DE ALBA
申请号：
IL24803016
公开号：
IL248030A
申请日:
2016.09.25
申请国别(地区):
IL
年份:
2019
代理人:
摘要：
The present invention relates to novel cannabidiol quinone derivatives of formula (I) (I) wherein R is the carbon atom of a, linear or branched group, represented by: alkyl, aryl, alkenyl, alkynyl, acyl or alkoxycarbonyl groups； or wherein R is the nitrogen atom of a, linear or branched group represented by: alkylamine, arylamine, alkenylamineor alkynylamine groups. The invention also relates to the use of any of the compounds of formula (I)as medicamentsin therapy, particularly for treating diseasesand conditions responsive to PPARg modulationdue to their high PPARg agonistic effect lacking electrophilic (Nrf2 activation) and cytotoxic activities. This invention also provides pharmaceutical compositions comprising said compounds and method of treating diseases with said compounds.
