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FORMULATIONS A LIBERATION PROLONGEE ET A RETENTION GASTRIQUE DE BERGENIA CILIATA
专利权人:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
发明人:
BHARATE, SONALI SANDIP,SINGH, ROHIT,GUPTA, MEHAK,SINGH, BIKARMA,KATARE, ANIL KUMAR,KUMAR, AJAY,BHARATE, SANDIP BIBISHAN,VISHWAKARMA, RAM
申请号:
CA3077342
公开号:
CA3077342A1
申请日:
2018.09.11
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention is related to a novel gastroretentive swellable oral dosage form for sustained or delayed release of bergenin, a active constituent of Bergenia ciliata extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/ or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract of bergenin-rich Bergenia ciliata with polymers has resulted in a sustained release of extract in the stomach over a period of 16-24hrs. The said formulations are useful for the treatment of inflammatory diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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