The present invention provides a preparation with improved disintegration property, a preparation showing improved bioavailability of a medicament, production methods thereof and the like. A rapidly disintegrating preparation comprising granules comprising a medicament coated with a coating layer containing sugar or sugar alcohol； and a disintegrant. A production method of a rapidly disintegrating preparation including a step of producing granules comprising a medicament, a step of forming a coating layer containing sugar or sugar alcohol on the obtained granules and a step of mixing the coated granules with a disintegrant and molding the mixture.本發明提供一種具有改進的崩壞性之製劑，一種表現出改進之藥劑生物有效性的製劑，其製造方法等。一種由顆粒及崩壞劑所構成的迅速崩壞製劑，該顆粒係由含有糖或糖醇的被覆層所被覆的藥劑所構成。迅速崩壞製劑的製造方法包括製造由藥劑所構成的顆粒的步驟，在所得的顆粒上形成含有糖或糖醇的被覆層的步驟，及將被覆顆粒與崩壞劑混合而將該混合物壓模的步驟。
