Provided is a drug removal device for removing drugs from one or more pockets from among a plurality of pockets arranged in the short-side direction of a drug sheet, for example. The drug removal device is provided with: a sheet conveyance path (2) for conveying a PTP sheet (100)； an opening (26) for dropping drugs, which is formed orthogonal to the direction of conveyance of the PTP sheet (100)； a pocket-pressing part (3) for removing drugs from drug-accommodating pockets (100a) in the PTP sheet (100)； a raising part (4) for raising a push-out member (31) of the pocket-pressing part (3)； a sheet-fixing part (5) for pressing and fixing the PTP sheet (100)； a drug flow passage (6) for conducting drugs removed from the drug-accommodating pockets (100a) to a drug accommodation part； a conveyance with adjustment part (7) for adjusting the width of conveyance of the sheet conveyance path (2)； and an opening with adjustment part (8) for adjusting the width of the opening (26) for dropping drugs.
